As of May 2026, there are 404 SaaS companies based in Chicago. They have combined revenues of $10.2B and employ 60.1K employees. They've raised $6.2B in capital and serve 39.3M customers combined.
Sorting: Highest -> Lowest
Showing 10 of 404 companies ranked by annual revenue.
Chicago, Illinois, United States
A global real estate advisory firm offering a comprehensive suite of services, including portfolio management, brokerage advisory and project management
Chicago, Illinois, United States
Direct response advertising and retention marketing agency providing sophisticated solutions to clients ranging from startups to Fortune 500 brands
Chicago, IL, United States
Tempus is making precision medicine a reality by applying AI in healthcare, deriving insights from our expansive library of clinical data and molecular data. We enable physicians to make real-time, data-driven decisions to deliver personalized care and targeted therapies for patients through our analytical machine learning platform that uses the power of artificial intelligence in healthcare. We also work with partners to facilitate discovery, development, and delivery of optimized therapeutic options for patients through distinctive solution sets. Our mission is for each patient to benefit from the treatment of others who came before by providing the healthcare industry tools that learn as we gather more data. It’s About Time. For more information, visit tempus.com and follow us on Twitter (@TempusLabs).
Chicago, Illinois, United States
provider of marketing automation and customer experience automation (CXA) software
Chicago, Illinois, United States
IRI is a leading provider of big data, predictive analytics and forward-looking insights that help CPG, OTC healthcare, retailers and media companies to grow their businesses. With the largest repository of purchase, media, social, causal and loyalty data, all integrated on an on-demand cloud-based technology platform, IRI guides its clients around the world in their quests to remain relentlessly relevant, capture market share, connect with consumers and deliver market-leading growth.
Chicago, Illinois, United States
Relativity is a technology company that provides e-discovery software solutions for managing electronic data during legal proceedings.
Chicago, Illinois, United States
Hugo is transforming the future of a continent by re-envisioning the future of its work. We exist to provide BPO excellence to our customers by investing heavily in the very best of African talent. African communities currently reap less than 2% of a BPO market worth a staggering $430 billion annually. We are changing this. Specializing in digital and AI operations, omnichannel customer support, and trust and safety solutions for some of the world’s largest tech and media companies, we are providing the continent’s university-educated youth with the skills necessary to build a meaningful career in the global digital economy. All whilst delivering industry-beating excellence for our clients. As a culture, we’re Silicon Valley meets ECOWAS — English et en Français. We’re smart, dynamic, and ambitious. And we’re on a mission to win for our clients and for our people
Chicago, Illinois, United States
Provider of information technology services intended to address complex issues and capitalize on opportunities to help deliver better outcomes. The company's services use digital components such as analytics, mobility, social media, and smart-embedded devices to change customer experience journeys and internal processes and offer end-to-end implementation, development and support services in the select industries of banking and financial services, retail and manufacturing, enabling customers transform technology portfolios from systems of record to launch pads of innovation.
Chicago, Illinois, United States
advanced visibility and automation solutions for the supply chain industry
Each Tuesday, we reverse-engineer a real SaaS company's revenue, profit, CAC, funnels, and its top growth tactic.
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